Matrix-assisted laser desorption/ionization for simultaneous quantitation of (acyl-)carnitines and organic acids in dried blood spots. | acylcarnitines, carnitines, organic acids | HRAM MS |
An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM). | insulin, insuline analogs | HRAM MS |
Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry. | anionic metabolites | HRAM MS |
Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells. | polo-like kinase 1, BI6727, Volasertib, BRAF, V600E | HRAM MS |
A strategy for sensitive, large scale quantitative metabolomics. | metabolomics | HRAM MS |
Proteomic and functional investigation of the colon cancer relapse-associated genes NOX4 and ITGA3. | NOX4, ITGA3 | HRAM MS |
Simultaneous quantification of Sphingolipids in small quantities of liver by LC-MS/MS | sphingolipids | Triple Quadrupole MS |
Underivatized oxysterols and nanoLC-ESI-MS: A mismatch. | oxysterols | HRAM MS, Triple Quadrupole MS |
Accurate and reliable quantification of 25-hydroxy-vitamin D species by liquid chromatography high-resolution tandem mass spectrometry. | 25-hydroxy vitamin D | HRAM MS |
Detection and quantification of proteins in clinical samples using high resolution mass spectrometry. | protein, biomarker | HRAM MS |
High speed capillary zone electrophoresis-mass spectrometry via an electrokinetically pumped sheath flow interface for rapid analysis of amino acids and a protein digest. | amino acid, proteins | HRAM MS |
Targeted Metabolomic Analysis of Head and Neck Cancer Cells Using High Performance Ion Chromatography Coupled with a HRAM MS HF Mass Spectrometer. | targeted metabolomics | HRAM MS |
MS2PIP prediction server: compute and visualize MS2 peak intensity predictions for CID and HCD fragmentation. | prediction models for fragmentation | HRAM MS |
Analysis of Cell Metabolism Using LC-MS and Isotope Tracers. | metabolism | HRAM MS |
Measurement of Lung Phosphatidylcholines in Exhaled Breath Particles by a Convenient Collection Procedure. | phosphatidylcholines | Triple Quadrupole MS |
Metabolism of human insulin after subcutaneous administration: A possible means to uncover insulin misuse. | insulin, insulin metabolites | HRAM MS |
Histamine quantification in human plasma using high resolution accurate mass LC-MS technology. | histamine | HRAM MS |
Sensitive, Simple, and Robust Nano-Liquid Chromatography-Mass Spectrometry Method for Amyloid Protein Subtyping. | amyloid protein | HRAM MS |
Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry. | oxysterols | HRAM MS |
In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant. | α-pyrrolidinopentiothiophenone | HRAM MS |
Altered Levels of Visinin-Like Protein 1 Correspond to Regional Neuronal Loss in AlzheimerDisease and Frontotemporal Lobar Degeneration. | visinin-like protein | Triple Quadrupole MS |
Development and Evaluation of a Parallel Reaction Monitoring Strategy for Large-Scale Targeted Metabolomics Quantification. | metabolites | HRAM MS |
Quantitation of a PEGylated protein in monkey serum by UHPLC-HRMS using a surrogate disulfide-containing peptide: A new approach to bioanalysis and in vivo stability evaluation of disulfide-rich protein therapeutics. | PEGylated protein | HRAM MS |
Dynamics of Protein Expression Reveals Primary Targets and Secondary Messengers of Estrogen Receptor Alpha Signaling in MCF-7 Breast Cancer Cells. | protein, estrogen receptor | HRAM MS, Triple Quadrupole MS |
Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery. | thromboxane | Triple Quadrupole MS |
Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease. | APOE, apolipoprotein | Triple Quadrupole MS |
Associations between calcium-phosphate metabolism and coronary artery calcification; a cross sectional study of a middle-aged general population. | parathyroid hormone (PTH) and 25-hydroxyvitamin D | Triple Quadrupole MS |
Transfer of developmental neurotoxin β-N-methylamino-l-alanine (BMAA) via milk to nursed offspring: Studies by mass spectrometry and image analysis. | BMAA, neurotoxin | Triple Quadrupole MS |
Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring | angiotensin II-regulated proteins | Triple Quadrupole MS |
Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. | carboxyl ester lipase (CEL) | Triple Quadrupole MS |
An analytical strategy to investigate Semen Strychni nephrotoxicity based on simultaneous HILIC-ESI-MS/MS detection of Semen Strychni alkaloids, tyrosine and tyramine in HEK 293t cell lysates. | semen strychini alkaloids, tyrosine, tyramine | HRAM MS |
Simultaneous Determination of Multiple Intracellular Primary Metabolites by Ultrahigh Performance Liquid Chromatography Coupled with a HRAM MS HF Mass Spectrometer. | primary metabolites | HRAM MS |
Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. | biomarkers, polar metabolites, lipids | HRAM MS |
Oxidative stress leads to reduction of plasmalogen serving as a novel biomarker for systemic lupus erythematosus. | plasmalogen | Triple Quadrupole MS |
25C‐NBOMe and 25I‐NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high‐resolution mass spectrometry | 25C-NBOMe, 25I-NBOMe | HRAM MS |
Determination of amino acids in colon cancer cells by using UHPLC-MS/MS and [U-13C5]-glutamine as the isotope tracer. | amino acids | Triple Quadrupole MS |
Identification and Characterization of Cardiac Troponin T Fragments in Serum of Patients Suffering from Acute Myocardial Infarction. | biomarker, cardiac troponin T | HRAM MS |
Identification and quantitation of phosphatidylethanols in oral fluid by liquid chromatography-tandem mass spectrometry. | phospatidylethanol | Triple Quadrupole MS |
A Nontargeted UHPLC-HRMS Metabolomics Pipeline for Metabolite Identification: Application to Cardiac Remote Ischemic Preconditioning. | biomarkers | HRAM MS |
Expanding the knowledge on dried blood spots and LC-MS-based protein analysis: two different sampling materials and six protein targets. | protein | HRAM MS, Triple Quadrupole MS |
Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure. | protein, biomarker | HRAM MS |
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK. | fructose 1,6-biphosphate, aldose mediate glucose | Triple Quadrupole MS |
Quantification of xanthine- and uric acid-related compounds in urine using a "dilute-and-shoot" technique coupling ultra-high-performance liquid chromatography and high-resolution Orbitrap mass spectrometry. | xanthine, uric acid | HRAM MS |
Holistic Lipidomics of the Human Gut Phenotype Using Validated Ultra-High-Performance Liquid Chromatography Coupled to Hybrid Orbitrap Mass Spectrometry. | fatty acyls, glycerolipids, phosphoglycerolipids, polyketides, prenols, saccharolipids, sphingolipids, sterols | HRAM MS |
Lower plasma choline levels are associated with sleepiness symptoms. | choline | Triple Quadrupole MS |
Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaMSites to Activation. | AMPK | Triple Quadrupole MS |
Easy, Fast, and Reproducible Quantification of Cholesterol and Other Lipids in Human Plasma by Combined High Resolution MSX and FTMS Analysis. | cholesterol, glycerolipids, sphingolipids, sterol esters | HRAM MS |
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells. | peptides | Triple Quadrupole MS |
Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing. | amino acid, lipid | Triple Quadrupole MS |
Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry. | dinnutuximab | Triple Quadrupole MS |
N6-(2-Deoxy-d- erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5- N-(2-hydroxy-3-buten-1-yl)-formamidopyrimidine Adducts of 1,3-Butadiene: Synthesis, Structural Identification, and Detection in Human Cells. | nucleobase adducts | Triple Quadrupole MS |
Rapid detection and quantification of aminoglycoside phosphorylation products using direct‐infusion high‐resolution and ultra‐high‐performance liquid chromatography/mass spectrometry | aminoglycoside phosporylation products | HRAM MS |
Neuronal pentraxin receptor-1 is a new cerebrospinal fluid biomarker of Alzheimer's disease progression. | pentraxin receptor | Triple Quadrupole MS |
Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry. | fatty acids | HRAM MS |
Bioactive Lipids in Sputum of Older Adults with Asthma as Potential Markers of Disease Phenotypes | lipids | Triple Quadrupole MS |
How do cancer-sniffing dogs sort biological samples? Exploring case-control samples with non-targeted LC-Orbitrap, GC-MS, and immunochemistry methods. | biomarkers, polar metabolites, lipids | HRAM MS |
A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography coupled to hybrid orbitrap high-resolution mass spectrometry. | biomarkers | HRAM MS |
Rapid analysis of pyridinoline and deoxypyridinoline in biological samples by liquid chromatography-mass spectrometry and silica hydride column. | pyridinoline, deoxypyridinoline | HRAM MS |
Performance of the MasSpec Pen for Rapid Diagnosis of Ovarian Cancer. | lipids | HRAM MS |
Plasma free metanephrines for diagnosis of neuroblastoma patients. | metanephrines, plasma free metanephrines | Triple Quadrupole MS |
Strain-Level Differentiation of Bacteria by Paper Spray Ionization Mass Spectrometry. | bacteria | HRAM MS |
Metabolomic profiling suggests systemic signatures of premature aging induced by Hutchinson-Gilford progeria syndrome. | untargeted, amino acids, sphingolipids, fatty acids | HRAM MS, Triple Quadrupole MS |
An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC-Q-Exactive High-Resolution Mass Spectrometry and a 1,1-Diphenyl-2-picrylhydrazyl-Based Assay. | biomarkers | HRAM MS |
Plasma metabolites Xanthine, 4-Pyridoxate, and d-glutamic acid as novel potential biomarkers for pulmonary tuberculosis. | biomarkers | HRAM MS |
Comparative analysis of the serum proteome profiles of thyroid cancer: An initial focus on the lipid profile. | proteomes, lipids | HRAM MS |
Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry | amatoxins | HRAM MS |
Biomedical copper speciation in relation to Wilson's disease using strong anion exchange chromatography coupled to triple quadrupole inductively coupled plasma mass spectrometry. | copper, ceruloplasmin | ICP-MS |
Characterization of a 7 kDa pollen allergen belonging to the gibberellin-regulated protein family from three Cupressaceae species | pollen allergen | HRAM MS |
Establishing reference intervals for urine and serum iodine levels: A nationwide multicenter study of a euthyroid Chinese population. | iodine | ICP-MS |
Evaluation of the first immunosuppressive drug assay available on a fully automated LC-MS/MS-based clinical analyzer suggests a new era in laboratory medicine | immunosuppressants | Clinical Analyzer |
High-precision isotopic analysis of serum and whole blood Cu, Fe and Zn to assess possible homeostasis alterations due to bariatric surgery. | copper, iron, zinc | ICP-MS |
LC-HRMS based approach to identify novel sphingolipid biomarkers in breast cancer patients | spingolipids | HRAM MS |
Metabolism Study of N-Methyl 2-amino Indane (NM2AI) and Determination of Metabolites in Biological Samples by LC-HRMS | N-methyl-2-aminoindane | HRAM MS |
Purity determination of synthetic glucagon using a mass balance approach | glucagon | HRAM MS |
Simultaneous determination of gastric cancer biomarkers pepsinogen PGI/PGII using element tagged immunoassay coupled with inductively coupled plasma mass spectrometry detection. | pepsinogen, element tagged immunoassay | ICP-MS |