NanoDrop Products Guide

Pipette. Measure. Know.

Quantify DNA, RNA and protein samples in seconds with only 1–2 µL using Thermo Scientific NanoDrop instruments. Whether you choose a NanoDrop UV-Vis spectrophotometer or fluorospectrometer, you can rely on patented* NanoDrop technology for accurate, fast results to assess sample concentration and purity. 

Choose the NanoDrop instrument that's right for you

Simplify DNA, RNA, and protein quantitation with direct sample measurement.

 NanoDrop One/Oneᶜ
NanoDrop 8000
NanoDrop Lite
NanoDrop 3300
NanoDrop 2000/2000c
Full-spectrum microvolume UV-Vis measurements with a cuvette option in a single instrument

Higher throughput, full-spectrum microvolume UV-Vis measurements

Basic microvolume UV measurements

Full-spectrum microvolume fluorescence measurements

Full-spectrum microvolume UV-Vis measurements; cuvette option available
Measures 1-2 μL sample

Dynamic range (ng/μL dsDNA)2.027,500*
ng/μL for dsDNA
ng/μL for dsDNA
ng/μL for dsDNA
< 1 fmol
ng/µL for dsDNA
Full-spectral data


Pre-programmed methods for nucleic acids and proteins

Measures nucleic acid A260/A280 ratio


Measures nucleic acid A260/A230 ratio


Measures purified protein A280


Measures protein A260/A280 ratio


Pre-programmed methods for colorimetric assays (BCA, Bradford, Lowry, Pierce 660)


Measures protein and peptides at A205


Custom methods


Built-in cuvette option


Standalone local control



High-resolution touchscreen interface

Measures fluorescently-labeled nucleic acid and protein samples using absorbance


Measures a wide variety of fluorescence assays: RiboGreen™, PicoGreen™, GFP, BFP mutants, Hoechst, 4-MU, Quantum Dots, OPA, DyLite™, Alexa Fluor™, etc.   

Measures multiple fluorophores from a single sample   

Auto-Measure capability

Contaminant identification

Embedded technical support

Password protected access


Enhanced connectivity (Wi-Fi and Bluetooth™)

Thermo Fisher Connect (Cloud enabled)


* lowest detection limit is 0.2 ng/μL with 10 mm cuvette

Move one step closer with next-generation microvolume UV-Vis

Be more successful in downstream applications when you qualify your sample before use with the NanoDrop One UV-Vis spectrophotometer built with novel Thermo Scientific Acclaro Sample Intelligence Technology.

For research use only. Not for diagnostic purposes. Bluetooth is a registered trademark of Bluetooth SIG, Inc. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries. All NanoDrop instruments are approved to CE and UL/CSA.

* Patents US6628382 and US6809826.