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Quantify DNA, RNA and protein samples in seconds with only 1–2 µL using Thermo Scientific NanoDrop instruments. Whether you choose a NanoDrop UV-Vis spectrophotometer or fluorospectrometer, you can rely on patented* NanoDrop technology for accurate, fast results to assess sample concentration and purity.
Simplify DNA, RNA, and protein quantitation with direct sample measurement.
NanoDrop One/Oneᶜ UV-Vis | NanoDrop 8000 UV-Vis | NanoDrop Lite UV | NanoDrop 3300 Fluorescence | NanoDrop 2000/2000c UV-Vis | |
![]() Full-spectrum microvolume UV-Vis measurements with a cuvette option in a single instrument | ![]() Higher throughput, full-spectrum microvolume UV-Vis measurements | ![]() Basic microvolume UV measurements | ![]() Full-spectrum microvolume fluorescence measurements | ![]() Full-spectrum microvolume UV-Vis measurements; cuvette option available | |
Measures 1-2 μL sample | ✓ | ✓ | ✓ | ✓ | ✓ |
Dynamic range (ng/μL dsDNA) | 2.0–27,500* ng/μL for dsDNA | 2.5–3,700 ng/μL for dsDNA | 4–1,500 ng/μL for dsDNA | < 1 fmol (FITC) | 2–15,000 ng/µL for dsDNA |
Full-spectral data | ✓ | ✓ | ✓ | ✓ | |
Pre-programmed methods for nucleic acids and proteins | ✓ | ✓ | ✓ | ✓ | ✓ |
Measures nucleic acid A260/A280 ratio | ✓ | ✓ | ✓ | ✓ | |
Measures nucleic acid A260/A230 ratio | ✓ | ✓ | ✓ | ||
Measures purified protein A280 | ✓ | ✓ | ✓ | ✓ | |
Measures protein A260/A280 ratio | ✓ | ✓ | ✓ | ||
Pre-programmed methods for colorimetric assays (BCA, Bradford, Lowry, Pierce 660) | ✓ | ✓ | ✓ | ||
Measures protein and peptides at A205 | ✓ | ✓ | |||
Custom methods | ✓ | ✓ | ✓ | ✓ | |
Built-in cuvette option | ✓ | ✓ | |||
Standalone local control | ✓ | ✓ | |||
High-resolution touchscreen interface | ✓ | ||||
Measures fluorescently-labeled nucleic acid and protein samples using absorbance | ✓ | ✓ | ✓ | ||
Measures a wide variety of fluorescence assays: RiboGreen™, PicoGreen™, GFP, BFP mutants, Hoechst, 4-MU, Quantum Dots, OPA, DyLite™, Alexa Fluor™, etc. | ✓ | ||||
Measures multiple fluorophores from a single sample | ✓ | ||||
Auto-Measure capability | ✓ | ||||
Contaminant identification | ✓ | ||||
Embedded technical support | ✓ | ||||
Password protected access | ✓ | ✓ | ✓ | ✓ | |
Enhanced connectivity (Wi-Fi and Bluetooth™) | ✓ | ||||
Thermo Fisher Connect (Cloud enabled) | ✓ | ✓ |
* lowest detection limit is 0.2 ng/μL with 10 mm cuvette
Be more successful in downstream applications when you qualify your sample before use with the NanoDrop One UV-Vis spectrophotometer built with novel Thermo Scientific Acclaro Sample Intelligence Technology.
For research use only. Not for diagnostic purposes. Bluetooth is a registered trademark of Bluetooth SIG, Inc. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries. All NanoDrop instruments are approved to CE and UL/CSA.
* Patents US6628382 and US6809826.