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Gibco™ Dynabeads CD3/CD28 CTS Magnetic Beads

It is used for isolation, activation and amplification of human T-cells in vitro. The first FDA-approved Novartis KymriahTM CAR-T cell therapy to fight B-cell precursor ALL, adopting Thermo Fisher Scientific CTS Dynabeads technology.

Invitrogen™ CTS DynaMag Magnet Large-Volume Sorting Magnetic Stand

It is used in combination with Dynabeads CD3/CD28 CTS in clinical studies to remove Dynabeads magnetic beads from T-cells after in vitro stimulation/amplification.

Thermo Scientific™ Heraeus Cyrofuge 8 Large-Capacity Floor-standing Centrifuge

The large capacity allows isolation of peripheral blood cells by centrifugation of 24×200ml blood bags at 7144×g, which meets the experimental standards of cell therapy. It features a highly sensitive touch screen that can be operated with gloves on, as well as one-button automated lid opening/closing function and built-in data management function, providing an excellent centrifugation solution for standardized cell therapy laboratories.

Gibco™ CTS™ Rotea™ Counterflow Centrifugation System

Gibco™ CTS™ Rotea™ Counterflow Centrifugation System is a flexible, scalable and closed cell processing system suitable for cell therapy production. It applies the mature counterflow centrifugation method to a wide range of cell processing applications, such as CAR T-cell therapy, stem cell therapy and PBMC isolation. The CTS Rotea system contains a compact multifunctional instrument, a single-use sterile kit, and the intuitive, visualized and customizable program software. Together, they constitute a closed system that provides excellent cell recovery rate, flexible input and output volumes, and efficient processing capabilities. It is ideal for a series of processes in your workflow, including cell isolation, concentration, washing, buffer replacement, and cryopreservation.

Invitrogen™ TrueCut™ Cas9 Protein

The new generation of Cas9 protein can provide higher gene editing efficiency, and has always been superior in efficiency for targets that are difficult to deal with in immune and primary cells.

Invitrogen™ Neon™ Electroporation Transfection System

The Invitrogen Neon™ Electroporation Transfection System delivers DNAs, RNAs and proteins to a variety of blood cell lines and primary T-cells, achieving a transfection efficiency of 90%.

Invitrogen™ Lipofectamine™ 3000 Transfection Reagent

The efficient and economical lentiviral production tool for adherent cells enables high viral titer even for large or hard-to-package genes. With the excellent transfection efficiency, it can raise the transfection efficiency of hard-to-transfect cells by 10 times.

Thermo Scientific™ Nunc™ Cell Factory™

It is widely used in large-scale cell culturing and the preparation of bioactive substances, which can effectively save the acclimation and linear amplification time required by large-scale cell culturing, meanwhile minimizing contamination, especially suitable for the preparation of viruses.

Thermo Scientific™ Sorvall WX+ UltraCentrifuge Series

It enables higher centrifugation yield and safer centrifugation operation with its compact appearance, self-balancing rotor, and a maximum speed of 100,000 rpm, which meets the experimental requirements on lentivirus isolation and collection. The lightweight and durable Fiberlite™ carbon fiber rotor does not need to be used at a reduced speed.

Glibco™ LVmax™ Lentiviral Production System

It is able to obtain a high-titer virus yield greater than 1×108 TU/ml (unconcentrated). The system is serum-free and is the first complete lentivirus suspension production system.

Thermo Scientific™ Single-Use Bioreactor

The 50L single-use bioreactor (SUB) provides a culture volume of 10-50L. It has been verified to be suitable for various cell lines, such as HEK293, CHO, SP20 hybridoma, NS0, PER.C6, Vero, MDCK, etc.

CTS TrypLE™ Select

It is a recombinant protease that complies with the new regulations of the National Center for Drug Evaluation (CDE) for cell therapy product process and has particular advantages in this application:

• Free of any animal- or human-derived ingredients, with little difference between batches
• The activity is consistent with that of animal-derived pancreatin
• Avoid potential risks of viruses and prions
• The full name of the product is traceable and the drug master file is filed with FDA

Thermo Scientific™ Nalgene™ Conical Culture Flask

It is made of lightweight, crack-resistant and transparent PETG, with available options of various sizes of vented or non-vented conical culture flasks, which are flat-bottomed with or without baffle. They are used on the benches or oscillators, achieving consistent performance in the cultivation of various cell types.

Gibco TrypLE™ Select Enzyme

It is a highly purified non-animal recombinant enzyme that can be an alternative for porcine or bovine trypsin for digestion of adherent cells such as HEK293 cells, mesenchymal stem cells and iPSC. It acts mildly on cells and does not require trypsin inhibitors; it can be stored at room temperature and is easy to use.

Gibco™ CTS™ AIM V™ Medium

It is the first commercial T-cell and dendritic cell proliferation and treatment product with a serum-free formula with defined components, and is produced in strict accordance with cGMP standards. This medium is an FDA Class II medical device. The drug master file has been submitted to the FDA.

Gibco™ CTS™ OpTmizer™ T-cell Expansion Medium

It is a serum-free, xeno-free medium suitable for the growth and expansion of human T lymphocytes, and is produced in strict accordance with cGMP standards. This medium is an FDA Class II medical device. The drug master file has been submitted to the FDA.

Gibco™ CTS™ Immune Cell Serum Replacement (SR)

It is a xeno-free formula with definite components, which can be added to standard basal media as a substitute for human serum. It is produced in strict accordance with cGMP standards. The drug master file has been submitted to the FDA.

Gibco™ CTS™ Cytokine and Growth Factor

It is a high-quality growth factor and cytokine used for T-cell, stem cell and dendritic cell applications. The production of CTS cytokines and growth factors meets the requirements of FDA 21 CFR Part 820: Medical Devices Quality System Regulation (QSR). Growth factors are produced in compliance with ISO 12485:2003 Medical Devices - Quality Management System - Requirements for Regulatory Purposes. The drug master file has been submitted to the FDA.

Thermo Scientific™ Forma/Heracell Carbon Dioxide Incubator and Cell Locker™ Chamber

It provides a clean space with contamination prevention and control function through the proven technology of high-temperature dry heat/moist heat sterilization, and has a variety of upgrade combinations, such as built-in shakers and independent space management solutions.

Thermo Scientific™ 1300 Series A2 Biological Safety Cabinet

Strict contamination control; unique Smartflow™ airflow system; SmartClean patented front window cleaning position design; comfortable armrest and low noise.

Finesse SmartBag/Smart Rocker

SmartBags can accommodate the cultures at 10-50L; SmartRocker can provide great wave angles to suspend high-density culture cells.

Applied Biosystems™ 7500 Fast Dx Real-Time PCR Instrument

It is based on semiconductor refrigeration technology (Peltier thermoelectric module technology) to deliver the performance required for high-quality results in the form of 96-well plates. It can identify 5,000 to 10,000 genomic equivalents (2 times copy number difference) with a confidence level of 99.7%.

Applied Biosystems™ MycoSEQ™ Mycoplasma Detection Kit

High sensitivity and various detection types, meeting the requirements of USP, EP, JP and ICH.

Applied Biosystems™ 3500 Series Genetic Analyzer

It performs fragment analysis and Sanger sequencing, including but not limited to STR/microsatellite analysis, loss of heterozygosity, SNP validation and screening, and ab initio sequencing and resequencing (mutant spectrum analysis). It provides dual-mode functions and is more flexible; it is equipped with powerful and integrated data acquisition and preliminary analysis software, which allows real-time data quality evaluation; it is simple to set up, operate and maintain.

Invitrogen™ Countless™ II FL Automated Cell Counter

The benchtop cytometer is equipped with advanced optical components and image analysis software for automated focusing and rapid counting of suspended cells. It is suitable for cells of size 7-60 μm to be counted with this method.

Thermo Scientific™ CellInsight CX7 High-Content Screening (HCS) System

High-resolution automated cell quantification imaging and analysis; used for high-throughput screening of effective T-cell chimeras; efficiently evaluating the killing efficiency of CAR T-cells (the percentage of targeted tumor cells killed), and automatically exporting the analytical data.

Invitrogen™ Attune™ NxT Flow Cytometer

It is a brand-new benchtop flow cytometer with innovative acoustic focusing technology, flexible configuration, up to 4-laser and 14-color system, which is fast and unblocked.

Thermo Scientific™ Multiskan ET Kinetic Endotoxin Detector

It adopts a patented optical system and single-channel detection, with a detection wavelength range of 340-850nm, which meets the detection requirements of a variety of limulus/tachypleus amebocyte lysate reagents, and can perform kinetic chromogenic and kinetic turbidimetric detection to ensure high accuracy of readings.

Thermo Scientific™ Varioskan LUX Multimode Microplate Reader

It integrates multiple optical detection technologies, including light absorption, fluorescence, chemiluminescence, time-resolved fluorescence and Alpha, which can meet the detection needs of multiple quality control indicators such as cell viability, toxicity, proliferation, and reporter gene expression.

Thermo Scientific™ Q Exactive Ultra High-Resolution Liquid Chromatography-Mass Spectrometry (LC-MS)

It identifies, confirms and quantifies non-target or target compounds and proteins in a quick and reliable way, and is especially suitable for cell therapy mechanism research, new target discovery and verification, quality control research, and drug packaging material detection.

Thermo Scientific™ Vanquish Ultra High-Performance Liquid Chromatography (HPLC)

Built with biologically inert materials, it is more suitable for the isolation and detection of biological sample analysis; with better retention time stability, excellent sensitivity and isolation efficiency, it is designed to meet strict engineering standards, and is adaptable to various detectors, which is especially suitable for cell therapy quality control research and detection of drug packaging materials and dextran 40.

Thermo Scientific™ VersaTREK Automated Microbial Culture System

The automated microbial culture system is approved by FDA and CFDA. With its unique barometric pressure sensor technology and VorTREXing™ vortex culture technology, positive results can be obtained more quickly and sensitively, helping to reduce the risk of microbial contamination.

Thermo Scientific™ GENEPURE Ultrapure Water Meter

Thermo Scientific™ 88880005 Hot Plate

Thermo Scientific™ 88880018 Vortex Oscillator

Thermo Scientific™ Finnpipette F1 Single Channel (Multichannel) Pipette

Thermo Scientific™ S1 Pipette Filler

Thermo Scientific™ PLR-3864°C Laboratory Refrigerator

Thermo Scientific™ Cyromed Controlled-Rate Freezer

It offers high flexibility of controlled-rate freezing where multiple freezing curves can be customized according to specific solutions.

Thermo Scientific™ CyroExtra40 High-Efficiency Gas Phase Liquid Nitrogen Tank/CyroPlus Liquid Nitrogen Storage Tank

Large storage capacity: 20,000 to 90,000 cryopreservation tubes; gas phase storage, preventing tube bursts, with extremely low probability of contamination; good thermal insulation performance: -190°C ±5°C; liquid nitrogen consumption is equivalent to that of a small liquid nitrogen tank.

Thermo Scientific™ Forma Ultra-Low Temperature Freezer

50% energy saving; quiet, 20 times quieter than traditional Ultra-Low Temperature freezers; long warranty period, 5-year warranty for the whole machine; it is environmentally friendly and uses fluorine-free hydrocarbon refrigerants (ethane and propane), which meets K6 standards.

Thermo Scientific™ Arctic Express Sample Transport Tank

The unique material absorbs liquid nitrogen and ensures the transportation of samples at low temperatures below -160°C without any risk of liquid nitrogen leakage. The cryopreservation time is 7-21 days. A dedicated IATA certified high-risk sample transport tank is available.