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PEP-210 is a 15 amino acid synthetic peptide. The sequence of this peptide is (amino to carboxy terminus: C A (120) L Q F G E E D A D P G A M (21).
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog # PA1-1962. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis tissue sperm binding protein Li 11n; macropain subunit zeta; Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; proteasome (prosome, macropain) subunit, alpha type, 5; proteasome alpha 5 subunit; proteasome component 5; Proteasome subunit alpha type-5; proteasome subunit zeta; Proteasome zeta chain
基因别名: PSC5; PSMA5; ZETA
UniProt ID: (Human) P28066
Entrez Gene ID: (Human) 5686