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产品信息
RP-96623
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
LSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPD
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (71%), Rat (71%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83374. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
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生物信息学
蛋白别名: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; KAT/AadAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; L kynurenine/alpha aminoadipate aminotransferase; Methionine--glyoxylate transaminase AADAT
基因别名: AADAT; KAT2; KATII; KYAT2
UniProt ID: (Human) Q8N5Z0
Entrez Gene ID: (Human) 51166
