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Highest antigen sequence indentity to the following orthologs: Mouse (55%), Rat (55%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60866. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1, 581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ABC-type organic anion transporter ABCA8; ATP-binding cassette sub-family A member 8; ATP-binding cassette, sub-family A (ABC1), member 8
基因别名: ABCA8; KIAA0822
UniProt ID: (Human) O94911
Entrez Gene ID: (Human) 10351