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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57423. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acyl-Coenzyme A oxidase 3 also know as pristanoyl-CoA oxidase (ACOX3) is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acyl-Coenzyme A oxidase 3, pristanoyl; Branched-chain acyl-CoA oxidase; BRCACox; Peroxisomal acyl-coenzyme A oxidase 3; Pristanoyl-CoA oxidase
基因别名: ACOX3; BRCOX; PRCOX
UniProt ID: (Human) O15254
Entrez Gene ID: (Human) 8310