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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60604. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: a disintegrin and metalloproteinase; ADAM; ADAMs; ADAMTS-like 5; ADAMTS-like protein 5; ADAMTSL-5; metalloendopeptidases; Thrombospondin type-1 domain-containing protein 6; thrombospondin, type I, domain containing 6
基因别名: ADAMTSL5; THSD6
UniProt ID: (Human) Q6ZMM2
Entrez Gene ID: (Human) 339366