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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: amyloid beta (A4) precursor protein-binding, family B, member 3; amyloid precursor interacting protein; Amyloid-beta A4 precursor protein-binding family B member 3; FE65-like protein 2; Fe65L2; Protein Fe65-like 2
基因别名: APBB3; FE65L2; SRA
UniProt ID: (Human) O95704
Entrez Gene ID: (Human) 10307