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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57742. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Rho GTPase-activating protein 10; Rho GTPase-activating protein 21; Rho-GTPase activating protein 10; Rho-type GTPase-activating protein 21
基因别名: ARHGAP10; ARHGAP21; KIAA1424
UniProt ID: (Human) Q5T5U3
Entrez Gene ID: (Human) 57584