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Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57070. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Filaggrin is a structural protein that is crucial for in the development and maintenance of the skin barrier. This gene encodes a retroviral-like protease involved in profilaggrin-to-filaggrin processing. Expression is found primarily in the epidermis and inner root sheath of hair follicles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ASPRV1; Retroviral-like aspartic protease 1; SASPase; skin aspartic protease; Skin-specific retroviral-like aspartic protease; TAPS; TPA-inducible aspartic proteinase-like protein
基因别名: ASPRV1; MUNO; SASP; SASPase; Taps
UniProt ID: (Human) Q53RT3
Entrez Gene ID: (Human) 151516