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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61717. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A cyclase IV; Adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase 4; ATP pyrophosphate-lyase 4; KIAA4004
基因别名: AC4; ADCY4
UniProt ID: (Human) Q8NFM4
Entrez Gene ID: (Human) 196883