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This peptide corresponds to 14 amino acids near the carboxy terminus of human BAG1.
PEP-0381 can be used as a blocking peptide with polyclonal antibody PA5-20266.
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
基因别名: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933
Entrez Gene ID: (Human) 573