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Highest antigen sequence indentity to the following orthologs: Mouse (33%), Rat (33%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Apoptosis inducer NBK; apoptosis-inducing NBK; BBC1; Bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); bhikhari; BIP 1; BIP1; BP 4; BP4; cb 60; natural born killer
基因别名: BIK; BIP1; BP4; NBK
UniProt ID: (Human) Q13323
Entrez Gene ID: (Human) 638