Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51909. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; Peregrin; Protein Br140
基因别名: BR140; BRPF1
UniProt ID: (Human) P55201
Entrez Gene ID: (Human) 7862