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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60967. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene plays a role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair. The encoded protein may function to stabilize the Ku70/Ku80 heterodimer to facilitate the assembly and maintain the stability of the NHEJ complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Paralog of XRCC4 and XLF; Protein PAXX; XRCC4-like small protein
基因别名: C9orf142; PAXX; XLS
UniProt ID: (Human) Q9BUH6
Entrez Gene ID: (Human) 286257