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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52768. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CCDC67 (deuterosome assembly protein 1) is a key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. The protein interacts with CEP152 and recruits PLK4 to activate centriole biogenesis
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: coiled-coil domain containing 67; Coiled-coil domain-containing protein 67; Deuterosome assembly protein 1
基因别名: CCDC67; DEUP1
UniProt ID: (Human) Q05D60
Entrez Gene ID: (Human) 159989