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This peptide corresponds to 18 amino acids near the carboxy terminus of human SLAMF3.
PEP-1249 can be used as a blocking peptide with polyclonal antibody PA5-21135.
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD229; Cell surface molecule Ly-9; Lymphocyte antigen 9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T-lymphocyte surface antigen Ly-9
基因别名: CD229; CDABP0070; hly9; LY9; mLY9; SLAMF3
UniProt ID: (Human) Q9HBG7
Entrez Gene ID: (Human) 4063