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产品信息
RP-109109
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSP
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (38%), Rat (38%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140322. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
CDY2B encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.
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生物信息学
蛋白别名: chromodomain protein, Y chromosome, 2 related; Testis-specific chromodomain protein Y 2; testis-specific chromodomain protein Y protein 2 related; Y chromosome chromodomain protein 2B
基因别名: CDY; CDY2; CDY2A; CDY2B
UniProt ID: (Human) Q9Y6F7
Entrez Gene ID: (Human) 203611
