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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65371. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cohen syndrome protein 1; Intermembrane lipid transfer protein VPS13B; Vacuolar protein sorting-associated protein 13B
基因别名: CHS1; COH1; KIAA0532; VPS13B
UniProt ID: (Human) Q7Z7G8
Entrez Gene ID: (Human) 157680