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Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53667. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COFA1; Collagen alpha-1(XV) chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; endostatin-XV; restin
基因别名: COL15A1
UniProt ID: (Human) P39059
Entrez Gene ID: (Human) 1306