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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62046. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Collagen alpha-2(VIII) chain; collagen VIII, alpha-2 polypeptide; collagen, type VIII, alpha 2; Endothelial collagen
基因别名: COL8A2; FECD; FECD1; PPCD; PPCD2
UniProt ID: (Human) P25067
Entrez Gene ID: (Human) 1296