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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55831. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Int11; Integrator complex subunit 11; Protein related to CPSF subunits of 68 kDa; RC-68; related to CPSF subunits 68 kDa
基因别名: CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68
UniProt ID: (Human) B3KPR3
Entrez Gene ID: (Human) 54973