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Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63723. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: collomin; colmedin; FLJ23917; Gliomedin
基因别名: CLOM; COLM; CRG-L2; CRGL2; GLDN; UNC-112; UNQ9339/PRO34011
UniProt ID: (Human) Q6ZMI3
Entrez Gene ID: (Human) 342035