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Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84114. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CTDSP2 is one of several small CTD phosphatases (SCP). It has been proposed that SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes. In addition, expression of phosphatase CTDSP2 mRNA isenhanced in several cancer cell lines with amplification of the CTDSP2 and CDK4 genes, and CTDSP2 coamplifies with CDK4 in some primary sarcomas. CTDSP2 may contribute to the development of a subset of sarcomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2; NLI-interacting factor 2; Nuclear LIM interactor-interacting factor 2; Protein OS-4; SCP2; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2
基因别名: CTDSP2; NIF2; OS4; PSR2; SCP2
UniProt ID: (Human) O14595
Entrez Gene ID: (Human) 10106