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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-65337, PA5-140241. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
基因别名: CTNNBIP1; ICAT
UniProt ID: (Human) Q9NSA3
Entrez Gene ID: (Human) 56998