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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2A9; 5B10; CABP; CACY; CacyBP; Calcyclin; Calcyclin-binding protein; growth-inhibiting gene 5 protein; hCacyBP; PRA; RP1-102G20.6; S100A6; S100A6-binding protein; Siah-interacting protein; Siah-interacting protein (SIP)
基因别名: CACYBP; GIG5; PNAS-107; S100A6BP; SIP
UniProt ID: (Human) Q9HB71
Entrez Gene ID: (Human) 27101