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产品信息
PEP-1053
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 15 amino acids near the carboxy terminus of human TCC52.
PEP-1053 can be used as a blocking peptide with polyclonal antibody PA5-20939.
靶标信息
Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cancer/testis antigen 102; Centrosome-related protein TCC52; DDB1- and CUL4-associated factor 12; Testis cancer centrosome-related protein; WD repeat domain 40A; WD repeat-containing protein 40A
基因别名: CT102; DCAF12; KIAA1892; TCC52; WDR40A
UniProt ID: (Human) Q5T6F0
Entrez Gene ID: (Human) 25853
