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Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63798. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta protein 1; distal-less homeo box 7; distal-less homeo box 9; Homeobox protein DLX-4; Homeobox protein DLX-7; Homeobox protein DLX-8
基因别名: BP1; DLX4; DLX7; DLX8; DLX9; OFC15
UniProt ID: (Human) Q92988
Entrez Gene ID: (Human) 1748