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Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55713. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DM domain expressed in testis 1; DM domain expressed in testis protein 1; Doublesex- and mab-3-related transcription factor 1
基因别名: CT154; DMRT1; DMT1
UniProt ID: (Human) Q9Y5R6
Entrez Gene ID: (Human) 1761