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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52576. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Augurin; ECRG4; esophageal cancer related gene 4 protein; Esophageal cancer-related gene 4 protein
基因别名: C2orf40; ECRG4; UNQ761/PRO1508
UniProt ID: (Human) Q9H1Z8
Entrez Gene ID: (Human) 84417