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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-66700, PA5-67305. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fez family zinc finger protein 1; Zinc finger protein 312B
基因别名: FEZ; FEZF1; HH22; ZNF312B
UniProt ID: (Human) A0PJY2
Entrez Gene ID: (Human) 389549