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产品信息
RP-109716
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
LPSPHKRAPLQSRRLRQASSQAGRLWSRPPLNYFHLIALALRNSSPCGLNVQQIYSFTRKHFPFFRTAPEGWKNTVRHNLCFRDSFEKVPVSMQGGASTRPRSCLWKLTEEGHRRFAEEARALASTRLESIQQCMSQPD
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (54%), Rat (54%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144774. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 amino acids. FOX transcription factors play roles in determining cell fate during early development. FOXR1 (forkhead box protein R1), also known as FOXN5 (forkhead box protein N5) or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR1 may be involved the development of certain invasive carcinomas.
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生物信息学
蛋白别名: Forkhead box protein N5; Forkhead box protein R1; forkhead box R1 variant 1; forkhead box R1 variant 2
基因别名: DLNB13; FOXN5; FOXR1
UniProt ID: (Human) Q6PIV2
Entrez Gene ID: (Human) 283150
