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Highest antigen sequence indentity to the following orthologs: Mouse (63%), Rat (63%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56076. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl peptide receptor-like 1; FPR-like 1; Fpr-rs1; Fprl-1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin receptor; LXA4 receptor; N-formyl peptide receptor 2; RFP
基因别名: ALXR; FMLP-R-II; FMLPX; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090
Entrez Gene ID: (Human) 2358