Invitrogen

Human FREM2 Synthetic Peptide

产品信息

PEP-1096

应用

建议稀释比

已发表文章

对照试剂 (Ctrl)

Assay-dependent

阻断反应 (BLOCK)

Assay-dependent

产品规格

种属反应

Human

分类

Synthetic

类型

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

purified

保存液

PBS, pH 7.2, with 0.1% BSA

内含物

0.02% sodium azide

保存条件

-20°C

产品详细信息

This peptide corresponds to 19 amino acids near the carboxy terminus of human FREM2.

PEP-1096 can be used as a blocking peptide with polyclonal antibody PA5-20982.

靶标信息

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.

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