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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67443. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GABA(A) receptor; GABA(A) receptor subunit alpha-5; GABAAR subunit alpha-5; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 5; Gamma-aminobutyric acid receptor subunit alpha-5
基因别名: GABRA5
UniProt ID: (Human) P31644
Entrez Gene ID: (Human) 2558