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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52502. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glycerol-3-phosphate dehydrogenase 2 (mitochondrial); Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; testicular tissue protein Li 76
基因别名: GDH2; GPD2; GPDM; mGPDH
UniProt ID: (Human) P43304
Entrez Gene ID: (Human) 2820