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Highest antigen sequence indentity to the following orthologs: Mouse (38%), Rat (38%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65074. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
GSG2 (haspin) is a conserved kinase required for mitosis. GSG2 phosphorylates histone H3 and is viewed as a potential therapeutic target for oncology. GSG2 is required for normal alignment of chromosomes at metaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: germ cell associated 2 (haspin); Germ cell-specific gene 2 protein; H-haspin; Haploid germ cell-specific nuclear protein kinase; Serine/threonine-protein kinase haspin
基因别名: GSG2; HASPIN
UniProt ID: (Human) Q8TF76
Entrez Gene ID: (Human) 83903