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Highest antigen sequence indentity to the following orthologs: Mouse (27%), Rat (27%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-65367, PA5-64087. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes. Also to note is that this gene maps to the 3'-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cancer susceptibility gene HEPN1; HEPACAM opposite strand 1; Putative cancer susceptibility gene HEPN1 protein
基因别名: HEPN1
UniProt ID: (Human) Q6WQI6
Entrez Gene ID: (Human) 641654