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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82987. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
HIPK4 is a homeodomain-interacting protein kinase and has been demonstrated to phosphorylate p53. HIPK4 encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Homeodomain-interacting protein kinase 4; testicular tissue protein Li 87
基因别名: HIPK4
UniProt ID: (Human) Q8NE63
Entrez Gene ID: (Human) 147746