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This product is a GST-tagged recombinant protein corresponding to human IGF-1R, aa 1213-1367.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43kDa.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
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