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产品信息
PEP-1583
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 18 amino acids near the amino terminus of human KANK3.
PEP-1583 can be used as a blocking peptide with polyclonal antibody PA5-34540. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
靶标信息
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.
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生物信息学
蛋白别名: ankyrin repeat domain 47; Ankyrin repeat domain-containing protein 47; kidney ankyrin repeat-containing protein 3; KN motif and ankyrin repeat domain-containing protein 3
基因别名: ANKRD47; KANK3
UniProt ID: (Human) Q6NY19
Entrez Gene ID: (Human) 256949
