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产品信息
RP-88088
产品规格
种属
Human
Expression System
HEK293 cells
氨基酸序列
Human KLK13, amino acids Met1-Ile262 (Accession # NP_056411.1) with a C-terminal His-tag
标签
His-tag
分子量
28.38 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
活性
Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >200 pmoles/min/ µg. (Activation description: The proenzyme needs to be activated by Lysyl-Endopeptidase for an activated form)
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
Reconstituted with sterile deionized water to 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. The novel KLK gene, KLK-L4, is expressed in a variety of tissues including prostate, salivary gland, breast, and testis. Its expression is regulated by steroid hormones in breast cancer cell lines may be involved in the pathogenesis and/or progression of breast cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586J1923; kallikrein 13; Kallikrein-13; kallikrein-like gene 4; Kallikrein-like protein 4; kallikrein-related peptidase 13; KLK-13; KLK-L4
基因别名: KLK-L4; KLK13; KLKL4
UniProt ID: (Human) Q9UKR3
Entrez Gene ID: (Human) 26085
