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产品信息
PEP-0462
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 14 amino acids near the carboxy terminus of human KappaB ras-2
PEP-0462 can be used as a blocking peptide with polyclonal antibody PA5-20342.
靶标信息
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras-like protein 2
基因别名: kappaB-Ras2; KBRAS2; NKIRAS2
UniProt ID: (Human) Q9NYR9
Entrez Gene ID: (Human) 28511
