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Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66558. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. L-Myc gene ontology annotations include DNA binding function, DNA-binding transcription factor activity, RNA polymerase II-specific action, protein dimerization activity, and regulation of inner ear auditory receptor cell differentiation.
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蛋白别名: bHLHe38; Class E basic helix-loop-helix protein 38; l-myc-1 proto-oncogene; myc-related gene from lung cancer; Protein L-Myc; Protein L-Myc-1; V-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived
基因别名: BHLHE38; L-Myc; LMYC; MYCL; MYCL1
UniProt ID: (Human) P12524
Entrez Gene ID: (Human) 4610