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产品信息
RP-102170
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEP
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52056. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling. This complex is involved in the regulation of late endosomal traffic and cellular proliferation and plays a role in cellular host defense against Salmonella infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endosomal adaptor protein p14; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; Late endosomal/lysosomal Mp1-interacting protein; MAPBP-interacting protein; MAPKSP1 adaptor protein; Mitogen-activated protein-binding protein-interacting protein; mitogen-activated protein-binding protein-interacting protein (MAPBPIP); Ragulator complex protein LAMTOR2; roadblock domain containing 3; Roadblock domain-containing protein 3
基因别名: ENDAP; HSPC003; LAMTOR2; MAPBPIP; MAPKSP1AP; p14; Ragulator2; ROBLD3
UniProt ID: (Human) Q9Y2Q5
Entrez Gene ID: (Human) 28956
