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产品信息
PEP-1573
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 17 amino acids near the carboxy terminus of human MTERFD1.
PEP-1573 can be used as a blocking peptide with polyclonal antibody PA5-34530. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
靶标信息
Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
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生物信息学
蛋白别名: Mitochondrial transcription termination factor 3; MTERF domain containing 1; mTERF domain-containing protein 1, mitochondrial; mTERF3; Transcription termination factor 3, mitochondrial
基因别名: CGI-12; MTERF3; MTERFD1
UniProt ID: (Human) Q96E29
Entrez Gene ID: (Human) 51001
