Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62155. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KASH domain-containing protein 2; KASH2; MGC96690; nesprin 2; Nesprin-2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Syne-2
基因别名: EDMD5; KIAA1011; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; SYNE2; TROPH
UniProt ID: (Human) Q8WXH0
Entrez Gene ID: (Human) 23224