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产品信息
RP-101948
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
AEVKIAIRRLWSKKENPGRE
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (55%), Rat (55%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63724. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Olfactory receptors are G protein-coupled receptor proteins that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction cascade that leads to the production of cAMP via an olfactory-enriched adenylate cyclase. This event ultimately leads to transmission of action potentials to the brain and the subsequent perception of smell. OR4B1 (Olfactory receptor 4B1), also known as Olfactory receptor OR11-106, is a 309 amino acid multi-pass membrane protein that functions as an odorant receptor, effectively binding odor molecules and initiating the propagation of signals to the primary olfactory cortex.
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生物信息学
蛋白别名: Olfactory receptor 4B1; Olfactory receptor OR11-106; olfactory receptor, family 4, subfamily B, member 1; OST208
基因别名: OR11-106; OR4B1; OST208
UniProt ID: (Human) Q8NGF8
Entrez Gene ID: (Human) 119765
