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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56248. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PHACTR1 plays a role in cell motility and in the formation of tubules by endothelial cells. PHACTR1 also binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Further, PHACTR1 regulates PPP1CA activity and is required for normal cell survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC126575; MGC126577; Phosphatase and actin regulator 1; RPEL repeat containing 1
基因别名: dJ257A7.2; KIAA1733; PHACTR1; RPEL; RPEL1
UniProt ID: (Human) Q9C0D0
Entrez Gene ID: (Human) 221692